منابع مشابه
Pediatric Immunology and Vaccination
While the majority of scientific evidence indicates that foals are immunocompetent at birth, vaccination is complicated by interference by passively transferred maternal antibody. In addition, there is considerable clinical evidence of poor resistance to disease or response to primary vaccinations in the first year of life. Against this background it is critical to identify and develop potent v...
متن کاملMucosal Immunology and Oral Vaccination
The mucosal surfaces of the gastrointestinal and respiratory tracts represent the principal portals of entry for most infectious agents. Hence, the development of vaccination strategies capable of inducing protective immune responses at the mucosal sites is a priority. Since the mucosal surfaces are exposed to a wide variety of antigens, the mucosal immune system has to discriminate between har...
متن کاملM. tuberculosis: immunology and vaccination.
Tuberculosis is increasing. Current treatment regimens require at least 6 months, because latent or stationary phase organisms are difficult to kill. Such regimens do not achieve full compliance, and "directly observed therapy short course" (DOTS) is having less impact than expected. This worrying situation is aggravated by coinfection with human immunodeficiency virus (HIV), and by the increas...
متن کاملMicroenvironment and Immunology Exploiting the Mutanome for Tumor Vaccination
Multiple genetic events and subsequent clonal evolution drive carcinogenesis, making disease eliminationwith single-targeted drugs difficult. The multiplicity of gene mutations derived from clonal heterogeneity therefore represents an ideal setting for multiepitope tumor vaccination. Here, we used next generation sequencing exome resequencing to identify 962 nonsynonymous somatic point mutation...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Medical Bulletin
سال: 2002
ISSN: 1471-8391,0007-1420
DOI: 10.1093/bmb/62.1.15